Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. Unlike opioids, which bind to µ-opioid receptors while in the central anxious program, conolidine modulates alternate molecular targets. A Science Developments review found that conolidine interacts Using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. By https://whatischronicpain87660.link4blogs.com/59799353/the-ultimate-guide-to-alternative-natural-pain-relief-to-replace-traditional-painkillers