Within the LSD-bound crystal structure, the side chain of your lid residue L209EL2 sorts comprehensive hydrophobic contacts with both LSD and bordering residues in TMs III, IV, and V (Figure 4C). If the lid moved aside to show the binding pocket in simulation, a number of of such contacts broke. https://businessplug5-meo-dmtcart59440.digitollblog.com/34925192/everything-about-lsd-aztec-99