In this article, we demonstrate that conolidine, a natural analgesic alkaloid Employed in classic Chinese drugs, targets ACKR3, thereby delivering extra proof of the correlation involving ACKR3 and ache modulation and opening alternative therapeutic avenues with the procedure of Continual agony. Employed in common Chinese, Ayurvedic, and Thai drugs. https://vana267wyn2.wikibriefing.com/user