44 Furthermore, anergic cells normally keep a better susceptibility to apoptosis Except if anti-apoptotic proteins which include BCL2 are overexpressed, as is the situation for CLL cells.45 Without a doubt, most important therapeutic innovations developing in the final ten years are relevant to the inhibition of BCR and BCL2-mediated signaling. https://nigeld197bjr5.idblogz.com/profile