No effect of polymorphisms in catechol-O-methyltransferase was discovered to be affiliated with postoperative oxycodone intake. The pharmacodynamics of oxycodone is usually dependent on polymorphic enzymes CYP2D6 and CP3A. Having hydrocodone or oxycodone with antidepressants may result in a risky buildup from the brain chemical serotonin. They don't, however, bind to https://wockusa.com/product/akorn-promethazine-hydrochloride-and-codeine-phosphate-solution/